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Further, NAPQI is conjugated with glutathione to form acetaminophen-glutathione conjugate (APAP-SG) causing a significant glutathione depletion and oxidative stress leading to cell impairment or death (Jaeschke and Bajt 2006
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25 This process not only clears necrotic debris but also advances liver repair, opening new avenues for therapeutic strategies in liver repair and regeneration
[DOI] [PubMed] [Google Scholar] King T
Spine, 40, E1250E1256, 2015
Other phytochemicals, such as phytosterols [23], cardiotonic steroids [24], and cannabinoid derivates [25], have been experimentally demonstrated to pose antitumor effects
