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doi:10.1046/j.1523-1747.1999.00607.x Mulder GD, Patt LM, Sanders L, et al

We found an increment in MBP expression between CPZ + 40 Hz compared with CPZ control mice in different brain areas (cortex, CC, and striatum), supporting a protective role of GENUS against CPZ-induced demyelination throughout multiple brain regions and CC tracts

This positioning is not accidental

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Note the profound effects on NO signaling and VEGF expression as well as several impacts on inflammatory cytokines