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B3 (niacin) assists in the function of the digestive system, skin, and nerves, and is also important for the conversion of food to energy

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It also repairs the intestinal mechanical barriers (Occludin and ZO-1) and the intestinal microbiota, showing the potential for multidimensional regulation of the inflammation-oxidation-barrier-microbiota axis

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The maintenance of a functional colonic mucosal barrier is essential to guarantee a healthy condition and the luminal confinement of bacteria is one of the key roles of the gut mucosa