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10.5414/CP201968 Int

Another function of Tau is revealed by its presence in the nucleus, where it has been reported to play roles in heterochromatin organization and chromatin stability by binding and interaction with heterochromatin, as well as modifying the liquidliquid phase separation (LLPS) characteristic of chromatin components (Abasi et al., 2024)

The Food and Drug Administration also hasnt approved it

In terms of vaccine design, maintaining the pre-fusion conformation of Env is an oft-encountered problem in the design of recombinant Env proteins as potential immunogens 27,28,29

The World Health Organization has for months argued that countries should pause booster shots for most people until a greater share of people around the world had received their first and second doses a message that fell on deaf ears in wealthy nations that pushed forward with booster campaigns

Whether this translates to humans is unresolved, so the label contraindicates it in the highest-risk groups as a precaution