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Tau oligomers bind to cardiolipin, and this binding leads to the creation of membrane pores, causing mitochondrial swelling, cytochrome c release, and a reduction in membrane potential (Camilleri et al., 2020)

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[DOI] [PubMed] [Google Scholar] 51.Basso DM, Beattie MS, Bresnahan JC

It has its own formula and schedule, depending on where you are

It represents the next generation of the CXXC5-targeting approach

Figure 1 Pathophysiology The pentose phosphate pathway, also known as the hexose monophosphate shunt, plays an important role in protecting cells from oxidative damage