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10.1016/j.jss.2011.06.033 J Surg Res

These include certain types of antibiotics (Tetracyclines, gyrase inhibitors, osteoporosis medications (bisphosphonates) and antirheumatic medications (d-Penicillamine)

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Furthermore, stabilization of NRF2 in cancer cells harboring oncogenic RAS induces genes encoding stress-responsive enzymes, including GPXs, NAD(P)H:quinone oxidoreductase-1 (NQO1), glutamate-cysteine ligase (GCL), GR, heme oxygenase-1 (HO-1), and glutathione S-transferase (GST), some of which are directly involved in cellular glutathione biosynthesis and ROS detoxification 22,23,24