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Tesoriere and colleagues developed a simulated in vitro model of the human intestinal epithelium using Caco-2 cell monolayers to mimic a functional barrier
Leppkes M, Knopf J, Naschberger E, Lindemann A, Singh J, Herrmann I, et al
Interactions with other drugs or supplements are currently unknown
M., Comstock R
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Furthermore, signal transducer and activator of transcription 3 (STAT3) can inhibit the mTOR/HIF-1 pathway by activating AMP-activated protein kinase (AMPK), leading to reduced cell proliferation and increased apoptosis (38)
