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Annual Review of Nutrition
In vivo, systemic NGB, myoglobin (MB), and CYGB administration in CCl-induced fibrosis dampened inflammation and slowed fibrogenesis without toxicity in treated mice, indicating a feasible safety window and a globin-based therapeutic class concept for fibrotic liver disease [112] (Figure 5)
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The Sdhc gene encoding a subunit of the succinate dehydrogenase enzyme, important in regulating electron flow through the ETC, was significantly upregulated in the AC-like cell state model, as were several thioredoxin genes involved in critical redox reactions ( Txn1, Txn2 ) (Fig
The analysis resolved order and disorder of individual protein domains nucleoporins within the nuclear pore complex (NPC) and showed that the tips of the FG domains are disordered, whereas the NPC-anchored domains are ordered (Mattheyses et al., 2010)
doi: 10.1016/j.eurpsy.2016.09.003
