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Both enzymes use molecular oxygen to mainly oxidize the diphenols present in grape must and wine such as caftaric and cutaric acids, catechin and other flavanols, anthocyanin, and flavanone, though laccase is able to oxidize a wider range of substrates than tyrosinase [5, 7, 8]

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The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARalpha-tr, autonomously regulates proliferative and pro-inflammatory genes

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