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Potency may decrease over time even with proper storage

Heres what most doctors wont tell you: approximately 84,000 chemical substances are currently in commercial use across the United States [8]

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10.1038/nature08389 Nature 204 YanJ.LiJ.-C.XieM.-L.ZhangD.QiA.-P.HuB.et al (2011)

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These naturally occurring peptides aid sleep regulation by modulating the hypothalamic activity, which is crucial for maintaining circadian rhythms
