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Aside from such examples of myelin/OLG relevant genes identified through GWAS, transcriptomic analyses reveal gene expression changes in additional myelin-related genes in a broad range of neurodegenerative diseases, including AD [3], PSP [3], MSA [82], and frontotemporal lobar degeneration (FTLD) [39], further supporting the idea of myelination changes as a common pathway across these diseases
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Am J Respir Crit Care Med 152(6):20842089 Gillery P, Leperre A, Maquart FX, Borel JP (1992) Insulin-like growth factor-I (IGF-I) stimulates protein synthesis and collagen gene expression in monolayer and lattice cultures of fibroblasts
Components of the ascorbate-glutathione cycle have been identified in the cytoplasm, mitochondria, and peroxisome, where it functions as an antioxidant defense system [309]
Alpha diversity metrics, such ACE, Chao, and Shannon indexes were calculated with Mothur (version 1.30.1)
18 Possible associations with diabetes, hypertension, and/or other cardiovascular conditions have been suggested, 11,16 but other studies have failed to corroborate these findings
