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Any references to biological activity are provided strictly for scientific research context only

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Another aspect of the present disclosure are deuterated compounds of Formula A and Formula B

In this sense, other studies have observed increased levels of TNF- in diabetic animal tissues (Satoh et al., 2003

Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRAS(G12C), are associated with renal toxicity in the Sprague Dawley rat