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Given that CDK5 and GSK-3 are strong tau kinases [50], this vicious cycle induced by palmitoyl-L-carnitine may result in a feedback loop of mitochondrial dysfunction and tau hyperphosphorylation, exacerbating AD pathology
doi: 10.1542/peds.2015-0129, PMID: [DOI] [PubMed] [Google Scholar] 81.Kpka A, Szajda SD, Waszkiewicz N, Pudowski P, Chojnowska S, Rudy M, et al
(2023) 12:e028892
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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Maruyama T., Maruyama N., Higuchi T
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