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Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine) J Biol Chem

Due to the short life span and sharply positive redox potential (~+2 V), its site of formation lies close to its point of reaction

Zhou, W.-Y
The glutathione response to glucose is biphasic between levels corresponding to diabetic patients and non-diabetic subjects, and switches rapidly between them at a critical glucose threshold

Timing Considerations The 3-minute half-life of AOD-9604 means the peptide is rapidly cleared from circulation, with peak effects occurring within the first hour post-administration

During drought stress, compartment specific changes in GSH and AsA contents were recorded
