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This is thought to be secondary to the cells ability to lie dormant, increase DNA repair and drug efflux capacity, and decrease apoptosis
For example, senior citizens are particularly vulnerable to alcohol because of age-related changes to their bodies

however, the clinical significance and durability of these effects remain under investigation

Wu Z, Li X, de Leeuw E, Ericksen B, Lu W: Why is the Arg 5 -Glu 13 salt bridge conserved in mammalian -defensins

Achieving optimal long-term glycemic control as well as reducing the risk of cardiovascular (CV), neurodegenerative diseases, and mortality continues to be a challenge for a significant portion of patients with type 2 diabetes (T2DM) and type 1 diabetes (T1DM) worldwide [8,9,10,11,12,13,14]

Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family