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14 Constraints of existing evidence Despite promising preclinical and early clinical findings, several limitations constrain the translation of apigenin and ellagic acid into mainstream PCOS therapy

In a first-in-human clinical study in healthy volunteers, AMG 966 elicited anti-drug antibodies (ADA) in 53 of 54 subjects (98.1%), despite a paucity of T cell epitopes observed in T cell assays

Smith-Palmer A, Stewart J, Fyfe L

Date palm kernel extract exhibits antiaging properties and significantly reduces skin wrinkles

Normal distribution was tested using D'Agostino & Pearson test and ShapiroWilk test

doi: 10.1007/s10787-024-01461-8, 111