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The imbalance between the production of reactive oxygen species (ROS) and the availability of antioxidants or free radical scavengers can cause oxidative stress, and that further activates an abundance of transcription factors and pro-inflammatory genes such as NF-B, p53, HIF-1, PPAR-, -catenin/Wnt, and Nrf2 [5,6,7]

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[DOI] [PubMed] [Google Scholar] 280.Inzinger M, Massone C, Arzberger E, Hofmann-Wellenhof R

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