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[DOI] [PubMed] [Google Scholar] Alonso, J.M

However, the use of plasmid-mediated siRNAs has limitations of rapid enzymatic degradation or unwarranted hyper-stimulated immune reaction and the most serious drawback was the random siRNA insertion into chromosomes [123]

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Acknowledgements L.W acknowledges the support of the NIH (R01GM118384 and R01CA258300)

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