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Hershey Medical Center
G.BayenE.et al
Serums 8.1.3
Levobupivacaine (LEV), a local anesthetic, can inhibit the expression of GPX4 and SLC7A11 by activating p53, thereby exerting a pro-ferroptosis effect and inhibiting the growth of tumors in vivo [104]
The regulation of HIFs is just one example of how ROS and cellular ratios of various TCA cycle metabolites, i.e., mitochondrial metabolism, can control gene expression and cellular responses (39)
Similarly, porcine collagen shows structural similarities with human collagen, resulting in wide use with minimal allergic responses [27]
