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Epigenetic Regulation NNMT activity consumes S-adenosylmethionine (SAM), the universal methyl donor required for hundreds of methylation reactions throughout the cell

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NICE guidance emphasises the importance of investigating the underlying cause of B12 deficiency rather than simply treating with supplements, as this may identify serious conditions requiring specific management

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TB-500 also exhibits clinically relevant anti-inflammatory properties through downregulation of inflammatory cytokines including TNF- and IL-1