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On the contrary, some reports demonstrated that high doses of exogenous GSH-reduced cisplatin induce neurotoxicity [37]

The primary antibodies employed were: P53 (Proteintech, 60283-2-Ig), pSer46-P53 (CST, 2521), FOXO4 (Proteintech, 21535-1-AP), P21 (CST, 2947), P16 (CST, 18769), BAX (CST, 2772), BCL2 (CST, 3498), Ki-67 (Proteintech, 84192-4-RR), Lamin B (CST, 13435), Cleaved Caspase 3 (CST, 9664), -H2AX (Abcam, ab81299), and GAPDH (Abcam, ab8245) as an internal reference for normalizing protein expression levels

Consequently, alternative approaches to increase endogenous testosterone without the disadvantages of TRT need to be developed

The therapeutic effects of dietary compounds are increasingly understood through metabolomic profiling, which reveals how these substances alter cellular metabolite compositions and metabolic pathway activities

Misiewicz, Z

Gowda VK, Kolli V, Benakappa A, et al