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In the case of compound 32 , the benzyl group can be seen extending towards the TIN2 phenylalanine binding pocket where it sits almost perpendicular to the naphthyl core (Supplementary Fig

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Phase II human trials of thymosin beta-4 (TB-500's parent molecule) have been conducted examining tissue repair rates, with studies reporting acceleration of repair in patients with pressure ulcers, stasis ulcers, and epidermolysis bullosa wounds, though detailed results remain limited in peer-reviewed literature

Bulletin of experimental biology and medicine, 165(1), 8083

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Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma