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We accept a lower success rate due to their simplicity and safety profile

For example, studies using CRISPR-based cytidine deaminase systems have successfully edited pathogenic mtDNA mutations in human cells, highlighting the therapeutic potential of these techniques (Schmiderer et al., 2022)

Allergy 68(6):702712

These findings support the rationale for initiating formal human clinical trials [83]

So I tend to do that at least three times a week

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