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Some patients experience ASCVD events despite achieving LDL-C goals, while others with apparently modest LDL-C elevations have high particle burden or inherited risk factors such as elevated Lp(a)

Note 1 , Note 3 The ratio of total cholesterol to high density lipoprotein cholesterol (TC:HDL-C) is also commonly used to assess a persons cardiovascular risk because it is an indicator of the amount of good cholesterol relative to the amount of total cholesterol

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A randomized controlled trial