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Clinically, gut microbiota-derived BCAAs synergize with PD-1 inhibitors to improve therapeutic responses in non-small cell lung cancer (NSCLC), potentially through microbiota-driven expansion of peripheral Tm cells and natural killer (NK) cell activation (Yao et al., 2023

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Chen J.G., Kensler T.W., Zhu J., Zhu Y.R., Wang J.B., Lu J.H., Muoz A., Groopman J.D

High expression of AKR1B10, also known as aldose reductase-like-1 (ARL-1), is seen in the adrenal glands, small intestine, and colon [11,15]

palpitations lasting more than 10 minutes continuously

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