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Ruenzi et al., 2005) and the experimental animal models (for review, see Sikiric et al., 2011

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BPC-157 administration attenuated gastric lesions, reduced esophagitis severity, strengthened anastomotic integrity, and markedly increased pressure at both the anastomotic site and pyloric sphincter

while normal dietary intake is considered safe, the effects of high-dose parenteral administration are less well studied
