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Genetic MC4R loss-of-function mutations cause severe hyperphagia and obesity, demonstrating the receptor's critical role in human energy balance

doi:10.1289/EHP10197

Williams, R

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and Wei et al., who reported that the composition of the fecal microbiota of patients with anti-NMDAR encephalitis significantly differed from that of healthy controls (6, 8, 11)

ALC treatment increases DA and 5-HT release and receptor activity while decreasing the 5-hydroxyindoleacetic acid (5-HIAA)/5-HT ratio, the latter representing lower 5-HT turnover (Sarzi-Puttini et al
