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N Engl J Med 354(6):567578 Heinemann V et al (2014) FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial

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PMID: 49 SakanoYSakanoKHurrellBPShafiei-JahaniPKazemiMHLiXet al

Oxidative stress is defined as an imbalance between the production of free radicals which are Reactive Oxygen Species (ROS) and antioxidants defences