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This is attributed to the heightened levels of NNMT potentially rendering NAM irretrievable, thereby constraining NAD + -dependent processes (Trammell and Brenner, 2015)
[15] Methionine donates methyl groups for the synthesis of S-adenosyl-methionine, which in turn drives phosphatidylcholine production and very-low-density lipoprotein assembly, facilitating export of triglycerides from hepatocytes and mitigating diet-induced steatosis

CAS 221231-10-3
doi: 10.1093/ajcn/70.5.928
