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Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists

In contrast to the patient with decompensated cirrhosis, hepatitis C antiviral therapy isclearly indicated in patients with compensated HCV-related cirrhosis, with preserved hepatic synthetic function who also have sufficient platelet and white blood cell counts to tolerate therapy (Table 7)

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doi: 10.1177/0333102410394675, PMID: [DOI] [PubMed] [Google Scholar] 51.Sangiorgi S, Mochi M, Riva R, Cortelli P, Monari L, Pierangeli G, et al
