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Another essential gene is MITF, which regulates the expression of melanogenic enzymes, such as tyrosinase

Atpenin A5 is of limited in vivo compatibility, and following its proof-of-concept as broad antiviral agents, more work is necessary to render it biocompatible or find other inhibitors of the same target

Treatment with pharmacological peroxisome proliferator-activated receptor agonist clofibrate causes upregulation of organic cation transporter 2 in liver and small intestine of rats

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid -peptide-associated free radical oxidative stress1, 2 1Guest Editors: Mark A, Smith and George Perry 2This article is part of a series of reviews on Causes and Consequences of Oxidative Stress in Alzheimer's Disease. The full list of papers may be found on the homepage of the journal

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doi: 10.1016/j.celrep.2019.05.019 73 ArmstrongAWWuJJohnsonMAGrapovDAziziBDhillonJet al