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Testing should also consider possible iron deficiency anaemia, macrocytosis, and take into account people on a vegan diet and individuals with a gastrointestinal disorder associated with a vitamin B12 deficiency (see Table 2)[17]

10.1016/j.ijbiomac.2023.126999 161 SunH.WangX.LiY.ShenY.ZhangL.XuY.et al (2024)

Intriguingly, polysome profiling indicated a significant impairment in the translation of CBS mRNA in DDX3X-deficient cells (Fig

A comprehensive panel of primary antibodies was used to detect various proteins: FOXO4, p53, Ser15-phospho-p53, p21 (cyclin-dependent kinase inhibitor 1A), p16 (cyclin-dependent kinase inhibitor 2A), 3-HSD, CYP11A1, CYP17A1 (cytochrome P450 family 17 subfamily A member 1), and several senescence-associated secretory phenotype (SASP) factors including IL-1, IL-1, IL-6, IL-10, TNF-, and TGF-

Accordingly, we can hypothesize that ferroptosis may serve to regulate normal epidermal differentiation during the pathophysiology of ichthyosis

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