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Increase in Solubility and Protease Resistance by -Glutamylation Gamma-glutamylation of cysteine has been reported to increase its water-solubility by threefolds (Hara et al., 1992)

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doi: 10.3390/molecules27196196

Cellular protection using Flt3 and PI3K inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity

Although tight junction permeability is increased in IBD, the extensive barrier loss seen in advanced, active disease is more likely to reflect epithelial damage 1216

Another very important source of ROS, including hydrogen peroxide and superoxide anion radicals are dynamic and metabolically active subcellular compartments, peroxisomes (Phaniendra et al
