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This activation triggers the phosphatidylinositol 3-kinase (PI3K)/Akt/eNOS cascade in vascular ECs [88]
Caspase-11 mediates pyroptosis of tubular epithelial cells and septic acute kidney injury
doi: 10.1002/mds.26117
Moreover, a comparative oncogenomic analysis identified that SHMT2, another mitochondrial gene involved in 1C metabolism, is amplified and is very important for tumor development [103]
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