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Supplementing with folic acid has been shown to reduce homocysteine levels

Combined nicotinamide N-methyltransferase inhibition and lean-diet substitution reduces body weight and liver fat in obese mice

Vet Res

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It is a major source for methyl groups via its metabolite trimethylglycine (betaine) that participates in the S-adenosylmethionine synthesis pathways

Neuron 111, 1529.e8
