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Moreover, it should be noted that the accumulation of fructose has been suggested to be more deleterious than that of glucose [75, 81] as fructose metabolism by fructokinase bypasses key-regulated steps of the glycolytic pathway [82] and thus can deplete intracellular phosphate and ATP, thereby inducing oxidative stress and inflammation [83]

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Rapid degradation in laboratory conditions makes dosing studies challenging

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A predictive biomarker for GHD should be developed in the future

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PMID: 39557185 Exp Cell Res 2026 Jun 9;461(1):115102

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Serious adverse reactions were rare

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Mesenchymal stem cells: clinical applications and biological characterization

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