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employed an acellular lung tissue to bio-fabricate functional islet organ, as shown in Figure 5 (85)

507 Furthermore, in a placebo-controlled trial of 91 participants (mean age 45 years) with low levels of macular pigment, a biomarker for levels of these carotenoids in the brain, daily supplementation with 10 mg lutein, 10 mg meso-zeaxanthin, and 2 mg zeaxanthin for 12 months significantly improved memory

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Further research is needed to validate Nrf2 activation in OA