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Alsaqati M, Heine VM, Harwood AJ

Mechanistically, GHK-Cu has been shown to stimulate collagen and elastin synthesis in dermal fibroblasts, increase decorin (a small proteoglycan that helps regulate collagen organization), and influence matrix metalloproteinases and their inhibitors

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118 Transient opening of the mPTP allows mitochondria to release excess ROS and Ca 2+ , preventing the harmful accumulation of these molecules

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