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Unlike PT-141 (bremelanotide), which was engineered for MC4R selectivity, MT-2 hits both receptors simultaneously

There is a strong association between the Carney complex and endocrine disease, including primary pigmented nodular adrenocortical disease (PPNAD)-associated Cushing syndrome, acromegaly, elevated prolactin, thyroid abnormalities, testicular large-cell calcifying Sertoli cell tumors, ovarian cystadenomas, and pancreatic lesions[99]

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and People's Medical Publishing House About this chapter Cite this chapter Zhou, Y., Jin, X., Chen, Q