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For AOD-9604, in vitro adipocyte data exist and are cited for elevated cAMP and HSL phosphorylation, but the cleanest mechanistic conclusions in the primary literature actually came from whole-animal and genetic experiments rather than from cell culture a reflection of how partly-indirect growth-hormone-type lipolysis can be

Epub 2006

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Studies of both GH replacement and GHRH analogs have not demonstrated an increase in cancer incidence or recurrence when used within physiologic ranges