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Currently, all three agents are approved for use in both first-line and subsequent treatment settings for patients with metastatic ER+/HER2 breast cancer [18]

Sestrin 2 protects against LPS-induced acute lung injury by inducing mitophagy in alveolar macrophages

System Xc is composed of the solute carrier family 7 member 11 (SLC7A11) and the solute carrier family 3 member 2 (SLC3A2)

GH and IGF-1 are also known to increase the expression of bone morphogenetic proteins 2 and 4 (BMP2, and BMP4) [88, 89], which are involved in mesoderm induction, skeletal patterning, and limb morphogenesis [9092]

While traditional concussion management focuses on rest and time, new insights into brain metabolism suggest a more active approachone that targets the energy crisis at the heart of the injury

A better understanding of the detailed interactions between the factors involved will contribute to further elucidate the cell defense capability, which is impaired in neurodegenerative diseases such as ALS [67, 141, 170], and may reveal the path for identifying novel potential therapeutic targets