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Leaky gut can cause many issues, including: allergies chronic fatigue syndrome depression fibromyalgia skin disorders increased food sensitivities and many more Damage to the intestinal epithelial lining has been associated with the following conditions: celiac disease Variety of autoimmune diseases inflammatory bowel disease (IBD) irritable bowel syndrome (IBS) ulcerative colitis Crohns disease multiple sclerosis rheumatoid arthritis type 1 diabetes Healing a leaky gut There are a number of steps you can take to heal your gut