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doi: 10.1172/JCI116109

Metal impurities cause false positives in high-throughput screening campaigns

In parallel, non-radical ROS, functioning as more stable, diffusible signaling molecules, can be therapeutically harnessed to combat infection and promote regeneration or, conversely, subverted to foster pathological processes like chronic inflammation, tumor progression, and age-related redox dyshomeostasis under abnormal flux regulation

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Another study, involving the pharmacological blocking of endogenous melatonin production in rats, observed an increase in tau hyperphosphorylation