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Urate induced dysregulation of immune cells potentially spurs the onset of HUA and the consequent complications, besides bolstering chronic inflammation

Although some studies have reported positive outcomes when using AOX therapy in conjunction with other fertility treatments, the evidence remains mixed, and large-scale RCTs are needed to confirm its efficacy and safety

Lancet 2015;386:7484

Among the oxidized nucleosides the majority of RNA oxidized species are present in the cytosol, not the nucleus or mitochondria

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