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The expression of CXCL13 is upregulated in tertiary lymphoid structures (TLS), particularly in areas characterized with significant B cell accumulation [82]

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Several scientific studies suggest that glutathione plays a role in longevity and healthier aging

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In another in vitro and in vivo study, Nrf2/HO-1 was also demonstrated to play an important inhibitory role in the pro-fibrotic pathway activated by TGF-1, which was verified by oligo-fucoidan in NRK-52E cells and kidney tissues of C57BL/6 mice [151]

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