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Description
Safe when properly dosed and integrated into an overall wellness plan
varies by formula) Evidence for weight loss: Limited What to know: Not standardized
However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program
doi: 10.1038/nrdp.2017.40
Funding This study was supported by the National Natural Science Foundation of China (No
O-GlcNAc modification of PPAR reduces its transcriptional activity
