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In the second one, it was proved that some genes have alternative splicing events and could be a mechanism to control AsA biosynthesis

Interestingly, MECP2 undergoes dynamic O-GlcNAc modification at threonine 203 (T203), and disruption of O-GlcNAcylation at this specific site in MECP2 impairs dendritic development and dendritic spine maturation in cultured hippocampal neurons, and dysfunction in synaptic transmission in the mouse cerebral cortex [117]

doi: 10.3390/FOODS12051052 122