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This occurred immediately upon the application of BPC 157 therapy in rats with occlusion/occlusion-like syndrome with permanent major vessel occlusion and similar noxious procedures that all severely affect endothelium function [24]

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Additional mechanistic studies demonstrated that both dihexa and Nle'-AnglV, its parent compound, were effective stimulators of hippocampal synaptogenesis thus providing a rational explanation for their pro-cognitive activities

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