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Mutational analysis of the N-terminus of AC6 as a regulatory domain showed that elimination of residues from 1 to 86 or a single mutation of Ser10 prevents phosphorylation and inhibition of AC6 by PKC (Figure 6) (Lai et al., 1999)

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We used this model to derive all companion photometry and flux limits in this work, including reconverting archival contrast curves to flux upper limits with this model

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After nebulization, the coloaded liposomes at a 30time lower dose of nintedanib show superior antifibrotic efficacy in rats compared to the oral nintedanib product