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Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response

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Compared with healthy individuals, those with established insulin resistance or type 2 diabetes might be more susceptible to the detrimental impacts of circadian disturbances on glucose metabolism [44, 45]

In addition to per and tim , CLK/ CYC heterodimers activate genes that participate in additional clock feedback loops and a substantial number of clock output genes [7], [8]

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Moreover, increased levels of oxidative stress markers were found in subacute post-stroke patients affected by NP [27]